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UKCTOCS: Ovaries, P-values & Questions

Ovarian cancer is a horrible disease.  It is often asymptomatic until late in its course and then causes a lot of suffering.  This is a disease with an extraordinarily high morbidity and currently has a 5-year survival of only 40%.  So wouldn’t it be excellent if we could find this disease early in it’s course, […]

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Clinical Case 117: Cancer Fishin’

OK – this case is for all the GPs and Internal Medicine types out there.  This is a relatively common scenario…  how do you play it? Here’s the case. Bruce is a 53 y.o. accountant.  He is a little overweight at 89 kg (BMI 31).  He is otherwise relatively well, he cycles to the cafe […]

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Hypercalcemia in a nutshell

Have seen a few patients with hypercalcemia recently and it has gotten me thinking.   It is one of those areas of medicine where the complex endocrine physiology and diseases can seem a bit overwhelming.  When we approach it in a practical sense it is much simpler than the head-spinning Med school lectures left us […]

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Mammography and pink cricket bats

A new review of the breast cancer screening ( mammography ) literature came out in the Lancet this week.  This is essentially an expert panel reviewing old data – nothing new.  The UK-based panel looked a the data from a number of long-running screening cohort studies and produced a set of round number estimates for the […]