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Sedation Agents for SAFE Sedation…

This is my Poor Man’s Psych pharmacy.  I have described each drug I use, when I use it and why.  Clearly there is more than one way to skin a cat, so make your own choices, but this is my simple cocktail bar….  I am more than happy to be corrected / chastised by anyone with more pharmacy knowledge than me – ie. pretty much anybody!  Most of this is OFF LABEL use – so there is not much evidence.

DRUG:  OLANZAPINE

WHENMy first line oral / sublingual antipsychotic.  It is good for sedation – especially for the true psychotic schizophrenic. Most of my medium to high risk patients get a dose if suitable.

WHYLove the sublingual wafer – you can see it go in!  Works quicker than oral.  NOt a classical – so no real EPSE.

 

DRUG:  QUETIAPINE

WHENSecond line oral antipsychotic.  I tend to use this when the patient is already on it, manic patients and for the mild / behavioural-based agitation where I use it PRN in place of benzos (esp. if they ask for them!!)

WHY: Sedating, can be titrated readily and given a bit more frequently

 

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